Say goodbye to tedious clinical WGS prep and unpredictable outcomes.
Why choose Callisto:
With Callisto, every run delivers the same high-quality libraries—regardless of operator skill level—thanks to pre-validated workflows, precision liquid handling, and tightly controlled processing conditions. This unmatched consistency means fewer repeats, cleaner data, and greater confidence in every result.
Consistently Superior Results
Callisto delivers highly uniform fragment sizes and cleaner libraries for every batch. Designed for high-quality, research-use sequencing workflows.
Fast Setup, Minimal Oversight
Automated, walk-away workflows help your team focus on higher-value tasks. Setup time, runtime, and throughput depend on the app and workflow.
Turnkey and Ready on Day One
Pre-loaded and pre-validated WGS workflows let you start sample preparation immediately—no method development, optimization, or costly trial-and-error. Callisto gets you from first run to production faster, accelerating your path to high-quality data and results. Focus on discoveries, not delays.
Effortless Operation with No Expertise Needed
A clean, intuitive interface and guided workflow mean even users with minimal lab experience can run complex WGS preparations. Push-button simplicity—load your samples, select your app, and walk away.
BROAD NGS COMPATIBILITY
Callisto also offers broad NGS compatibility for both long- and short-read sequencing—making it ideal for expanding your test menu without costly new equipment and method development investments.
Expanded Chemistry Compatibility
Callisto™ now supports library-preparation workflows for a wide range of leading whole-genome sequencing chemistries — including reagents from Illumina, New England Biolabs (NEB), Twist Bioscience, KAPA/Roche, Qiagen, and Watchmaker Genomics — all validated for use with multiple sequencers. Laboratories such as GeneDx are already utilizing Callisto’s chemistry-agnostic platform to streamline high-quality WGS operations across diverse reagent systems.
With this expanded flexibility, your lab can choose the chemistry AND sequencer that best match your workflow — without being locked into one system.
Built to Flex with Your Platform
Callisto delivers validated, high-quality library prep across all major sequencing platforms and chemistries—Illumina, Twist, NEB, KAPA, Qiagen, and Watchmaker. Whether you’re scaling clinical WGS testing or ensuring reproducible results across batches, Callisto gives you complete flexibility without compromising performance.
TRUSTED BY LEADERS IN GENOMICS
Callisto's walk-away automation, powered by advanced digital fluidics, is truly a game-changer. It allows our clinical technicians to simply load 24 DNA samples and produce sequencing-ready libraries seamlessly in <3 hours.”
Marcel Nelen
UMC Utrecht
CALLISTO VS. TRADITIONAL PREP
App-dependent
Workflow-dependent
Configuration-dependent
Workflow-dependent
Workflow-dependent
Configuration-dependent
RESOURCES
Powering Clinical Genetics at UMC Utrecht with Callisto
Past webinar — October 7, 2025
