The Callisto™ Sample Prep System. Right the first time.
Callisto automates extraction, library prep and hybrid capture on one benchtop system. A new chemistry is a kit you load, not a new instrument you buy.
Callisto is For Research Use Only. Not for use in diagnostic procedures. Oxford Nanopore products are RUO. Regulatory status and claims regarding third-party products are the responsibility of the third party.
A new chemistry is a kit you load, not a new instrument.
Add apps as kits on the Callisto™ you already have.
Each app is already automated on Callisto.
Load the kit and walk away.
Find the app for your workflow.
Filter by extraction, library prep or hybrid capture, then by sequencer.
New on Callisto: AXELIOS 1 Library Prep, in collaboration with Roche.
AXELIOS 1 Library Prep
50 ng of purified DNA in, sequencing-ready libraries out. About one hour of hands-on time, 4 to 24 samples per run.
View app →Oxford Nanopore Technologies LSK114
Automated LSK114 ligation sequencing library prep, with high molecular weight DNA extraction available on the same Callisto.
View app →High molecular weight DNA for long-read sequencing.
DNA extraction ahead of short-read library prep.
Library prep for AXELIOS 1 sequencing.
Ligation sequencing library prep.
SMRTbell library prep for HiFi sequencing.
Enzymatic fragmentation library prep.
Library prep for Illumina-compatible sequencing.
PCR-free library prep.
Enzymatic fragmentation library prep.
Enzymatic fragmentation library prep.
Enzymatic fragmentation library prep.
Hybridization capture for targeted sequencing.
Hybridization capture for targeted sequencing.
Hybridization capture for targeted sequencing.
Hybrid capture apps and DNA extraction for short-read sequencing are not tied to a single sequencer, so they show under All sequencers. Ask us about your sequencer.
Callisto is For Research Use Only. Not for use in diagnostic procedures. Oxford Nanopore products are RUO. Regulatory status and claims regarding third-party products are the responsibility of the third party.
The front end for the sequencers you already run.
Pick your sequencer to see which Callisto apps prepare samples for it.
Running something else, or planning to add a sequencer? Hybrid capture apps work on prepared libraries. Talk to us about your setup.
Book a demo
A walk-through of the instrument and the app menu with our team.
Book a demoTalk to us about your sequencer
Tell us what you sequence and we will show you which apps fit.
Talk to usLoad the kit. Walk away.
Load the app’s kit and your samples on Callisto.
Start the app on the touchscreen. Callisto runs it walk-away.
Take your output off the deck: extracted DNA, sequencing-ready libraries or captured libraries.
Run the next app on the same Callisto, or go straight to your sequencer.
Sized for a benchtop. Batches that match your runs.
On your bench
Callisto sits on a stable lab bench and runs on standard 100–240 VAC power. Full dimensions are in the specs below.
Up to 24 reactions per run
Up to 24 reactions per run is the platform maximum. Some apps run smaller batches; Twist Fast Hyb Cap runs 4 reactions per run.
Your sequencers
Library prep apps cover AXELIOS 1, Illumina, Oxford Nanopore, PacBio, Element and Ultima Genomics. See by sequencer
Hands-on time by app
Inputs and full specifications for every app are on each app’s page. AXELIOS 1 Library Prep and Oxford Nanopore products are For Research Use Only. Not for use in diagnostic procedures. Regulatory status and claims regarding third-party products are the responsibility of the third party.
Callisto product specifications
Physical
Power
Installation
Up to 24 reactions per run is the platform maximum. Some apps run smaller batches; Twist Fast Hyb Cap runs 4 reactions per run.
Go deeper on Callisto.
Method details and data for apps on Callisto.
Conference posters from the Volta Labs team.
Technical notes on the Callisto platform.
Product and workflow videos.
Recorded webinars on sample prep with Callisto.
News, notes and more in one place.
Questions about Callisto
What is the Callisto Sample Prep System?
Callisto™ is a benchtop sample prep system from Volta Labs that automates extraction, library prep and hybrid capture in walk-away runs, with 14 released apps. For Research Use Only. Not for use in diagnostic procedures.
What is a Callisto app?
An app is an automated protocol and the reagents you load on the same Callisto instrument, so adding a new chemistry or sequencing technology means buying a kit, not a new instrument.
Which sequencers do Callisto apps support?
Callisto library prep apps cover AXELIOS 1, Illumina, Oxford Nanopore Technologies, PacBio, Element and Ultima Genomics sequencing. Each app page lists its compatible sequencers.
How many reactions can Callisto run at once?
Callisto supports up to 24 reactions per run. Some apps run smaller batches; Twist Fast Hyb Cap runs 4 reactions per run.
How big is the Callisto instrument?
Callisto measures 66.8 cm (H) × 92.7 cm (W) × 84.6 cm (D), is 90 cm tall with the door open, weighs 70.3 kg and needs a stable lab bench and 100–240 VAC, 50/60 Hz power.
See Callisto in your lab.
Book a walk-through of the instrument and the app menu, or go straight to the apps themselves.
Callisto is For Research Use Only. Not for use in diagnostic procedures. Oxford Nanopore products are RUO. Regulatory status and claims regarding third-party products are the responsibility of the third party.